An improved surgical technique for pterygium excision with intraoperative application of mitomycin-C.
نویسندگان
چکیده
A surgical technique was designed to improve safety after pterygium excision with intraoperative application of mitomycin-C (MMC). A limbic incision was performed in 40 eyes. The body of the pterygium was dissected from the episclera to allow its excision. Care was taken to avoid excessive delamination and cauterization of tissues. A 0.02% MMC solution was then applied. Only at the end of the surgery was the head of the pterygium dissected from the cornea. The 8-0 absorbable sutures were used to place both edges of the conjunctiva together to completely cover the area of bare sclera. After a mean follow-up time of 12 months, a recurrence rate of 5% was observed. No complications of therapy were observed. This is a logical alternative to other surgical techniques. However, randomized studies with more patients and longer follow-up are necessary to determine the potential of this procedure in improving the safety of pterygium excision with intraoperative MMC.
منابع مشابه
Recurrence rate of pterygium following surgical excision with intraoperative versus postoperative mitomycin-C.
OBJECTIVE To compare the rate of recurrence and complications of pterygium following surgical excision by applying 0.02% mitomycin-C intraoperatively or using topical 0.02 % mitomycin-C drops postoperatively. STUDY DESIGN Randomized clinical trial. PLACE AND DURATION OF STUDY Baqai Medical University Hospital, Department of Ophthalmology, from January 2001 to July 2005. METHODOLOGY Eighty...
متن کاملمقایسهی تاثیر قطرهی میتومایسین Cحین و پس از عمل جراحی در عود، حدت بینایی و فشار داخل چشمی در جراحی ناخنک
Background and Objective: Pterygium is a common ocular surface disorder. A number of surgical procedures are used to remove it. The purpose of this study was to compare recurrent, visual acuity and intraocular pressure after pterygium surgery using mitomycin C during and after surgery. Materials and Methods: In this interventional study, 119 patients with indications for pterygium surgery were ...
متن کاملProspective trial of intraoperative mitomycin C in the treatment of primary pterygium.
AIMS A prospective, randomised, double blind, placebo controlled study of intraoperative mitomycin C as adjunctive treatment of primary pterygium was conducted. METHODS A total of 66 eyes of 54 patients with primary pterygium were treated with excision, with or without a single intraoperative application of mitomycin C (0.1 mg/ml for 5 minutes) to evaluate the efficacy and toxicity of this ad...
متن کاملIntraoperative application of 5-fluorouracil and mitomycin C aschemoadjuvants in primary pterygium surgery.
BACKGROUND/AIM To compare the effectiveness of intraoperative 5 fluorouracil (5-FU) and mitomycin C (MMC) application in preventing recurrence following primary pterygium excision. MATERIALS AND METHODS This was a prospective clinical trial that included 93 patients with primary pterygia assigned to three treatment groups in which 29 patients received an intraoperative application of 25 mg/mL...
متن کاملComparison of Results Excision through Bare Sclera Technique with and without Intraoperative Mitomycin C Application
.. Objective: To study the results of primary pterygium excision through bare sclera technique with and without intraoperative Mitomycin C use. Study design: This was an experimental study with randomised controlled trial. Setting and Duration: This study was conducted at Eye A unit, Khyber Teaching Hospital, Peshawar from May,2007 to April,2009. Methodology: One hundred patients with primary p...
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عنوان ژورنال:
- Ophthalmic surgery and lasers
دوره 29 8 شماره
صفحات -
تاریخ انتشار 1998